Cannabinoid Potency
Cannabinoids | Potency Analysis
Chemicals called cannabinoids, which are present in cannabis, influence users by interacting with particular central nervous system receptors. Each of the more than 100 distinct cannabinoids that have been documented in scientific literature has a distinct biological effect. The cultivation, harvesting, and processing of the plant all affect the cannabinoid makeup and potency, which differ amongst strains.
People can accurately assess the effectiveness and applicability of a given product by accurately analyzing cannabis strains and their corresponding cannabinoid ratios, such as THC to CBD. Expectations in the production and cultivation stages are reinforced by Sunrise Laboratories’ comprehensive cannabinoid profiling. Additionally, the consumer gains more confidence as a result of this higher level of strain identity confirmation.
Sample Size Required for Analysis: 3 grams
FAQs
Cannabinoids with acids, Because they undergo enzymatic transformation into the carboxylic acid precursors of other cannabinoids, CBGVA and CBGA are both regarded as “stem cell” cannabinoids. The carboxylic acid CBGA can change into THCA, CBDA, or other acidic cannabinoid precursors based on the enzymes it comes into contact with. Conversely, CBGVA changes into the precursors of different cannabinoids like CBCVA, THCVA, and CBDVA.
With a decarboxylation stage (heating cannabinoids at particular temperatures), acid cannabinoids can also be converted into active cannabinoids like Delta-9 THC.
Despite being one of the “big six” cannabinoids that are widely used in medical research, cannabichromene (CBC), which is non-psychoactive, doesn’t receive as much attention. CBC, the third most prevalent cannabinoid in cannabis, has very promising potential health benefits. It may even surpass the amount of cannabidiol (CBD) in certain cannabis strains. In addition to its various health-promoting qualities, CBC primarily interacts with TRPV1 and TRPA1 receptors.
Cannabidiol (CBD) is considered the second most researched cannabinoid in cannabis. CBD is a non-psychoactive cannabinoid that doesn’t have the same intoxicating psychoactive effects as Δ9-THC. CBD has been found to interact with a variety of different biological targets, including cannabinoid receptors and other neurotransmitter receptors.
Cannabigerol (CBG) is a non-psychoactive cannabinoid typically most abundant in low-THC, high-CBD cannabis strains. Like THC, CBG reacts with the cannabinoid receptors in the brain. It is known to be the only cannabinoid with the ability to stimulate the growth of new brain cells. CBG, however, acts as a buffer to the psychoactivity of THC, by working to alleviate the paranoia sometimes caused by higher levels of THC.
Cannabigerol (CBG) is a non-psychoactive cannabinoid typically most abundant in low-THC, high-CBD cannabis strains. Like THC, CBG reacts with the cannabinoid receptors in the brain. It is known to be the only cannabinoid with the ability to stimulate the growth of new brain cells. CBG, however, acts as a buffer to the psychoactivity of THC, by working to alleviate the paranoia sometimes caused by higher levels of THC.
Cannabicyclol, also called CBL, is one of the least known and studied cannabinoids in the cannabis plant. Although it is commonly found in many varieties, in particular those with a higher content of CBC (Cannabichromene), the amount of CBL produced in trichomes is always very low, so it doesn’t usually receive the attention given to other, more plentiful compounds of the plant with a much more noticeable presence, such as THC, CBD or CBN.
One of the main characteristics of CBL is the absence of psychoactivity in its effect. In fact, CBL shares its formula with many of the other phytocannabinoids produced by cannabis, even with psychoactive compounds, although it differs slightly in its structure meaning that its effects vary enormously.
Cannabinol (CBN) is a cannabinoid and effective compound that contributes to cannabis’ effects on the body and mind. CBN works as a psychoactive compound like THC does, but it has a milder impact. The reason for this is as TCH begins aging, it begins transforming into CBN. The benefit of this is, CBN mainly activates the CB2 receptors, which affect the immune system. It also interacts with the CB1 receptors to a lesser degree which work with the central nervous system.
Delta-8 is a cannabis compound that has become popular because of its similarity to delta-9 THC, the main compound in cannabis that gets you high, causing euphoria, happiness, sedation, symptom relief, and much more. Large amounts of THC are found in a majority of cannabis strains. The similarities between the two cannabinoids lie in their chemical structures and their names. THC’s scientific name is delta-9-tetrahydrocannabinol, or delta9 THC, or just delta-9. Delta-8 is short for delta-8-tetrahydrocannabinol, or delta-8 THC. The two THCs are chemically different in the placement of the double bond. Both cannabinoids have a chain of carbon atoms, but delta-8 has the double bond on the eighth carbon, whereas delta-9 has it on the ninth.
Delta-9-tetrahydrocannabinol (Δ9-THC) is a psychotropic cannabinoid and is one of the most commonly found cannabinoids in cannabis and gives one a euphoric felling. THC is one of few psychoactive cannabinoids that binds to CB1 & CB2 receptors in the body. This can produce a wide-range of biological and behavioral responses which can provide health and enjoyment benefits.
Delta-9-tetrahydrocannabinolic acid (Δ9-THCA), in the presence of specific enzymes, are converted into specific acids during the growth of the cannabis plant. For instance, The THCA synthase enzyme converts CBGA to tetrahydrocannabinolic acid within a catalytic step.
Since CBGA is converted to other acid cannabinoids during cannabis growth, it is commonly referred to as a “parental” cannabinoid. Acid cannabinoids (CBDA, CBCA, CBGA and THCA) can also be transformed into active cannabinoids (CBD, CBC, CBG, THC) given a decarboxylation step (heating cannabinoids at specific temperatures).
Δ9-Tetrahydrocannabivarin (Δ9-THCV or simply THCV) is a homolog of THC, and therefore these two cannabinoids have very similar chemical structures. It has been said that in small quantities THCV acts as an THC cannabinoid antagonist (THCV reduces THC effects), but in larger quantities THCV acts as a THC agonist (it bolsters or enhances its effects). THCV is found in high concentrations in African sativas.
The 140 phytocannabinoids that are extracted from cannabis include THCP. THCP, a naturally occurring analogue of THC, makes up 0.1% of the ratio. Tetrahydrocannabiphorol, or THCP, is a derivative of THC that has seven carbon atoms in an alkyl chain. When it comes to binding with the CB1 receptor, THCP has double the effects of THC, demonstrating thirty times greater potency.
Among the hundreds of cannabinoids present in hemp and cannabis plants, delta 10 is a trace amount. Only extremely little amounts of Delta 10 are found naturally in the early stages of the plant, in contrast to the most well-known cannabinoids including CBD, THC, and CBG. The cannabinoid recognized to be in charge of giving us the highs associated with cannabis is delta-9 THC. Where the bonds are located in their chemical structures is the primary distinction between Delta-9 and Delta-10; Delta-9’s bond is on the ninth carbon chain, Delta-8’s is on the eighth, and Delta-10’s is on the tenth.
exo-THC, also known as ∆9-11-THC, occurs as an impurity of ∆9-THC formed during its synthesis.
Tetrahydrocannabivarin Acid (THCVA) is the carboxylic acid precursor to tetrahydrocannabivarin (THCV), enzymatically biosynthesized as CBGVA is converted to THCVA. When THCVA is decarboxylated into THCV, it does not produce a psychoactive effect as does THCA when decarboxylated into THC. THCVA research is limited, but it is known to be a CB1 receptor antagonist and a CB2 receptor agonist as well as a modulator of various cation channels. Pharmacological research is limited but appetite suppression and anti-inflammatory effects may be among its properties.
THC-O is an ester of THC. It can be synthesized through a chemical process using acetic anhydride, a high-inflammable and colorless liquid used to make fibers, plastics, pharmaceuticals, dyes, and explosives.The production of this compound requires specialized equipment as it involves using volatile and flammable chemicals. The process to synthesize THC-O consists of extracting delta-8 THC from CBD extracted from the hemp plant. Finally, acetic anhydride is added to the delta-8 THC molecules to produce THC-O acetate. There is no confirmed data on how potent THC-O is. Several news publications report that THC-O is more potent than more popular THC as it is reported to be three times as powerful as THC.
Among the hundreds of cannabinoids present in hemp and cannabis plants, delta 10 is a trace amount. Only extremely little amounts of Delta 10 are found naturally in the early stages of the plant, in contrast to the most well-known cannabinoids including CBD, THC, and CBG. The cannabinoid recognized to be in charge of giving us the highs associated with cannabis is delta-9 THC. Where the bonds are located in their chemical structures is the primary distinction between Delta-9 and Delta-10; Delta-9’s bond is on the ninth carbon chain, Delta-8’s is on the eighth, and Delta-10’s is on the tenth.